2006 Mercedes-Benz E350Problems, recalls & complaints

NHTSA has logged 400 owner complaints about the 2006 Mercedes-Benz E350, most often about the fuel/propulsion system. It is covered by 4 safety recalls, and for recall 24V-874 the manufacturer reports only 10% of affected cars repaired.

2006 Mercedes-Benz E350

Source: NHTSA complaints, recalls, investigations and manufacturer recall reports, through October 15, 2026. Updated daily. Photo: Elise240SX, CC BY-SA 4.0.

Complaints by system

Where the 2006 Mercedes-Benz E350 has problems

400 complaints grouped by the system owners reported.

Box size = number of complaints naming that system. Darker = larger share. One complaint can name more than one system.
Complaints by system
SystemComplaintsCrash, fire or injury
Fuel/propulsion system1447
Fuel system, gasoline782
Engine507
Service brakes463
Power train372
Engine and engine cooling222
Electrical system191
Air bags135
Service brakes, hydraulic80
15 other systems548

Source: NHTSA Office of Defects Investigation. Complaints are submitted by the public and are not verified by NHTSA.

4 recalls

2006 Mercedes-Benz E350 recalls and how many were fixed

Each ring shows the share of affected cars repaired, from the manufacturer’s latest quarterly report to NHTSA. Recall repairs are free at authorized dealers.

10%repaired · 2026 Q3

Visibility: sun/moon roof assembly

Recall 24V-874 · Nov 19, 2024 · 33,456 vehicles · 3,406 repaired

Risk. A detached sunroof panel can become a road hazard, increasing the risk of a crash.

Problem, fix and repair progress →

34%repaired · 2025 Q4

Visibility: sun/moon roof assembly

Recall 22V-954 · Dec 23, 2022 · 131,653 vehicles · 45,331 repaired

Risk. A detached sunroof panel may become a road hazard, increasing the risk of a crash.

Problem, fix and repair progress →

46%repaired · 2023 Q2

Visibility: sun/moon roof assembly

Recall 21V-196 · Mar 19, 2021 · 11,356 vehicles · 5,200 repaired

Risk. A detached glass panel can separate from the vehicle and become a road hazard, increasing the risk of a crash.

Problem, fix and repair progress →

24%repaired · 2026 Q1

Visibility: sun/moon roof assembly

Recall 19V-918 · Dec 20, 2019 · 747,928 vehicles · 177,202 repaired

Risk. A detached glass panel can separate from the vehicle and become a road hazard, increasing the risk of a crash.

Problem, fix and repair progress →

Recalls apply to specific cars. To see whether a recall is still open on yours, enter the 17-character VIN at nhtsa.gov/recalls or with Mercedes-Benz.

Mileage at failure

When do fuel/propulsion system problems start?

97kmiles, median

Based on the odometer reading in 119 fuel/propulsion system complaints. 54% were reported before 100,000 miles.

median0k50k100k150k200k+
5under 30k miles64under 100k miles55100k miles or more
Owner-reported costs

What owners say repairs cost

Dollar amounts owners wrote in their complaints when describing a repair or a quote. These are not price estimates; a system is shown only when at least 8 owners mentioned a cost.

Fuel/propulsion system

15 owners mentioned a cost

$3,000median

Middle half: $2,000 – $3,455

Engine and engine cooling

12 owners mentioned a cost

$6,350median

Middle half: $4,800 – $7,250

Engine

8 owners mentioned a cost

$5,250median

Middle half: $3,563 – $6,625

If a problem is covered by a recall, the dealer fixes it for free. Some manufacturers also reimburse owners who paid for a repair before a recall was announced.

Best & worst years

2006 vs. every other E350 year

Bars show complaints per model year. Colors show the CarFlaw verdict: complaints weighted for crashes, fires and injuries, adjusted for years on the road and compared with the E350 median. How we score

'05'06'07'08'09'10'11'12'13'14'15'16'17'20'21'22'23'24'25'26
  • Avoid
  • Caution
  • Solid
  • Best
  • Not rated
2 investigations

NHTSA defect investigations

Federal investigations that included the 2006 Mercedes-Benz E350, and the recalls they led to.

  1. Fuel Leakage From The Fuel TankEA13003 · closed Dec 19, 2014
    No recall
  2. Driver Air Bag Circuit High ResistancePE10017 · closed Nov 24, 2010
    No recall
In owners' words

What E350 owners report

Recent fuel/propulsion system complaints filed with NHTSA, shortened. Personal details are removed.

PZEV fuel tank leaks at top but is not repairable. Replacement requires complete tank replacment which is not economically feasilble. This forces owners to continue to operate vehicle with fuel leakage since repair of the tank is not possible. In older models a simple gasket change would resolve…
Complaint 11512596 · Mar 19, 2023
I recently started smelling gas in my car after refueling. I was told by my mechanic that Mercedes was replacing fuel pumps and fuel tanks free of charge. Mercedes Benz customer care has advised this isn't so. This is an expensive repair and I am hoping Mercedes Benz can cover the cost of this…
Complaint 11497476 · Dec 14, 2022
In June 2017, I received a letter from Mercedes-Benz of America informing me that the warranty of the fuel system in my vehicle is extended to 15 years. In that same year, I had my whole fuel tank replaced by an authorized Mercedes Benz dealer in San Jose, California due to strong smell of fuel by…
Complaint 11493193 · Nov 11, 2022

Own a 2006 E350?

Decode your VIN to see the recalls for your exact car, then confirm open recalls with NHTSA.