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2010 Mercedes-Benz E350Problems, recalls & complaints

NHTSA has logged 185 owner complaints about the 2010 Mercedes-Benz E350, most often about the air bags. It is covered by 4 safety recalls, and for recall 22V-168 the manufacturer reports only 36% of affected cars repaired.

2010 Mercedes-Benz E350
51
CarFlaw IndexSolid year5% below the E350 median · #8 of 13 years by complaints
Safety recalls4Lowest repair rate 36%Owner complaints18514 with a crash, fire or injuryTypical failure mileage55kAir bags, median miles

Source: NHTSA complaints, recalls, investigations and manufacturer recall reports, through November 12, 2026. Updated daily. Photo: Elise240SX, CC BY-SA 4.0.

Complaints by system

Where the 2010 Mercedes-Benz E350 has problems

185 complaints grouped by the system owners reported.

Box size = number of complaints naming that system. Darker = larger share. One complaint can name more than one system.
Complaints by system
SystemComplaintsCrash, fire or injury
Air bags683
Fuel/propulsion system180
Suspension182
Electrical system172
Engine151
Power train141
Structure122
Service brakes110
Steering80
11 other systems336

Source: NHTSA Office of Defects Investigation. Complaints are submitted by the public and are not verified by NHTSA.

4 recalls

2010 Mercedes-Benz E350 recalls and how many were fixed

Each ring shows the share of affected cars repaired, from the manufacturer’s latest quarterly report to NHTSA. Recall repairs are free at authorized dealers.

36%repaired · 2024 Q1

Control module: software

Recall 22V-168 · Mar 18, 2022 · 22 vehicles · 8 repaired

Risk. Various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions including stability and traction control,…

Problem, fix and repair progress →

74%repaired · 2026 Q3

Passenger side: inflator module

Recall 18V-043 · Jan 10, 2018 · 132,167 vehicles · 97,355 repaired

Risk. An inflator explosion may result in sharp metal fragments striking the driver or other occupants resulting in serious injury or death.

Problem, fix and repair progress →

66%repaired · 2026 Q3

Passenger side: inflator module

Recall 16V-363 · May 26, 2016 · 258,163 vehicles · 169,998 repaired

Risk. An inflator rupture may result in metal fragments striking the vehicle occupants resulting in serious injury or death.

Problem, fix and repair progress →

65%repaired · 2026 Q3

Driver side: inflator module

Recall 16V-081 · Feb 11, 2016 · 711,159 vehicles · 464,166 repaired

Risk. In the event of a crash necessitating deployment of the driver's frontal air bag, the inflator could rupture with metal fragments striking the driver or other…

Problem, fix and repair progress →

Recalls apply to specific cars. To see whether a recall is still open on yours, enter the 17-character VIN at nhtsa.gov/recalls or with Mercedes-Benz.

Best & worst years

2010 vs. every other E350 year

Bars show complaints per model year. Colors show the CarFlaw verdict: complaints weighted for crashes, fires and injuries, adjusted for years on the road and compared with the E350 median. How we score

'05'06'07'08'09'10'11'12'13'14'15'16'17'20'21'22'23'24'25'26
  • Avoid
  • Caution
  • Solid
  • Best
  • Not rated
2 investigations

NHTSA defect investigations

Federal investigations that included the 2010 Mercedes-Benz E350, and the recalls they led to.

  1. Rear brake line failureDP20004 · closed Oct 9, 2020
    No recall
  2. Desiccated Air Bag Inflator RuptureEA21002 · still open
    Open
In owners' words

What E350 owners report

Recent air bags complaints filed with NHTSA, shortened. Personal details are removed.

I was involved in a head on collision when a motorist driving in the wrong lane hit the front of my car in the evening of 10/2/24. The impact was huge and my car was totaled. However, my airbag did not deploy and I hit my chest and knees very hard against the steering wheel and dashboard. Airbag…
Complaint 11624539 · Nov 11, 2024
TL* TAKATA RECALL. THE CONTACT OWNS A 2010 MERCEDES-BENZ E350. THE CONTACT RECEIVED RECALL NOTIFICATIONS FOR NHTSA CAMPAIGN NUMBERS: 18V043000 (AIR BAGS) AND 16V081000 (AIR BAGS). THE CONTACT STATED THAT THE MANUFACTURER EXCEEDED A REASONABLE AMOUNT OF TIME FOR THE RECALL REPAIRS. AN UNKNOWN DEALER…
Complaint 11267978 · Oct 11, 2019
TL* TAKATA RECALL. THE CONTACT OWNS A 2010 MERCEDES-BENZ E350. THE CONTACT RECEIVED A RECALL NOTIFICATION FOR NHTSA CAMPAIGN NUMBERS: 16V081000 (AIR BAGS) AND 18V043000 (AIR BAGS). THE CONTACT STATED THAT THE MANUFACTURER EXCEEDED A REASONABLE AMOUNT OF TIME TO REPAIR THE VEHICLE. GURLEY LEEP…
Complaint 11266086 · Oct 4, 2019

Own a 2010 E350?

Decode your VIN to see the recalls for your exact car, then confirm open recalls with NHTSA.